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Compromised respiratory function in lethal influenza infection is characterized by the depletion of type I alveolar epithelial cells beyond threshold levels

During influenza virus infection, it is unclear how much alveolar cell loss can be tolerated before the host succumbs to the disease. We sought to define relevant correlates of disease severity in the mouse influenza model, hypothesizing that a susceptibility threshold exists for alveolar epithelial...

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Detalhes bibliográficos
Main Authors: Sanders, Catherine J., Vogel, Peter, McClaren, Jennifer L., Bajracharya, Resha, Doherty, Peter C., Thomas, Paul G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627938/
https://ncbi.nlm.nih.gov/pubmed/23355384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00343.2012
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