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Compromised respiratory function in lethal influenza infection is characterized by the depletion of type I alveolar epithelial cells beyond threshold levels

During influenza virus infection, it is unclear how much alveolar cell loss can be tolerated before the host succumbs to the disease. We sought to define relevant correlates of disease severity in the mouse influenza model, hypothesizing that a susceptibility threshold exists for alveolar epithelial...

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Bibliografiska uppgifter
Huvudupphovsmän: Sanders, Catherine J., Vogel, Peter, McClaren, Jennifer L., Bajracharya, Resha, Doherty, Peter C., Thomas, Paul G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627938/
https://ncbi.nlm.nih.gov/pubmed/23355384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00343.2012
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