mTOR modulates the antibody response to provide cross-protective immunity to lethal influenza infections

Highly pathogenic avian influenza viruses pose a continuing global threat. Current vaccines will not protect against novel pandemic viruses. Creating “universal” vaccines has been unsuccessful because the immunological mechanisms promoting heterosubtypic immunity are incompletely defined. We show th...

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Main Authors: Keating, Rachael, Hertz, Tomer, Wehenkel, Marie, Harris, Tarsha L., Edwards, Benjamin A., McClaren, Jennifer L., Brown, Scott A., Surman, Sherri, Wilson, Zachary S., Bradley, Philip, Hurwitz, Julia, Chi, Hongbo, Doherty, Peter C., Thomas, Paul G., McGargill, Maureen A.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883080/
https://ncbi.nlm.nih.gov/pubmed/24141387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2741
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