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Alveolar Macrophages Prevent Lethal Influenza Pneumonia By Inhibiting Infection Of Type-1 Alveolar Epithelial Cells

The Influenza A virus (IAV) is a major human pathogen that produces significant morbidity and mortality. To explore the contribution of alveolar macrophages (AlvMΦs) in regulating the severity of IAV infection we employed a murine model in which the Core Binding Factor Beta gene is conditionally dis...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Cardani, Amber, Boulton, Adam, Kim, Taeg S., Braciale, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268648/
https://ncbi.nlm.nih.gov/pubmed/28085958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006140
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