A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites

Insertional mutagens such as viruses and transposons are a useful tool for performing forward genetic screens in mice to discover cancer genes. These screens are most effective when performed using hundreds of mice, however until recently a major limitation to performing screens on this scale has be...

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Bibliographische Detailangaben
Hauptverfasser: Uren, Anthony G., Mikkers, Harald, Kool, Jaap, van der Weyden, Louise, Lund, Anders H., Wilson, Catherine H., Rance, Richard, Jonkers, Jos, van Lohuizen, Maarten, Berns, Anton, Adams, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627465/
https://ncbi.nlm.nih.gov/pubmed/19528954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2009.64
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