High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors

Retroviral and transposon-based insertional mutagenesis (IM) screens are widely used for cancer gene discovery in mice. Exploiting the full potential of IM screens requires methods for high-throughput sequencing and mapping of transposon and retroviral insertion sites. Current protocols are based on...

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Dettagli Bibliografici
Autori principali: Koudijs, Marco J., Klijn, Christiaan, van der Weyden, Louise, Kool, Jaap, ten Hoeve, Jelle, Sie, Daoud, Prasetyanti, Pramudita R., Schut, Eva, Kas, Sjors, Whipp, Theodore, Cuppen, Edwin, Wessels, Lodewyk, Adams, David J., Jonkers, Jos
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2011
Soggetti:
Method
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227106/
https://ncbi.nlm.nih.gov/pubmed/21852388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.112763.110
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