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High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors

Retroviral and transposon-based insertional mutagenesis (IM) screens are widely used for cancer gene discovery in mice. Exploiting the full potential of IM screens requires methods for high-throughput sequencing and mapping of transposon and retroviral insertion sites. Current protocols are based on...

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書誌詳細
主要な著者: Koudijs, Marco J., Klijn, Christiaan, van der Weyden, Louise, Kool, Jaap, ten Hoeve, Jelle, Sie, Daoud, Prasetyanti, Pramudita R., Schut, Eva, Kas, Sjors, Whipp, Theodore, Cuppen, Edwin, Wessels, Lodewyk, Adams, David J., Jonkers, Jos
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227106/
https://ncbi.nlm.nih.gov/pubmed/21852388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.112763.110
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