High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors

Retroviral and transposon-based insertional mutagenesis (IM) screens are widely used for cancer gene discovery in mice. Exploiting the full potential of IM screens requires methods for high-throughput sequencing and mapping of transposon and retroviral insertion sites. Current protocols are based on...

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Detalhes bibliográficos
Main Authors: Koudijs, Marco J., Klijn, Christiaan, van der Weyden, Louise, Kool, Jaap, ten Hoeve, Jelle, Sie, Daoud, Prasetyanti, Pramudita R., Schut, Eva, Kas, Sjors, Whipp, Theodore, Cuppen, Edwin, Wessels, Lodewyk, Adams, David J., Jonkers, Jos
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
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Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227106/
https://ncbi.nlm.nih.gov/pubmed/21852388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.112763.110
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