Restricted Heterochromatin Formation Links NFATc2 Repressor Activity With Growth Promotion in Pancreatic Cancer

BACKGROUND & AIMS: Transcriptional silencing of the p15(INK4b) tumor suppressor pathway overcomes cellular protection against unrestrained proliferation in cancer. Here we show a novel pathway involving the oncogenic transcription factor nuclear factor of activated T cells (NFAT) c2 targeting a...

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Detalhes bibliográficos
Principais autores: BAUMGART, SANDRA, GLESEL, ELISABETH, SINGH, GARIMA, CHEN, NAI-MING, REUTLINGER, KRISTINA, ZHANG, JINSAN, BILLADEAU, DANIEL D., FERNANDEZ-ZAPICO, MARTIN E., GRESS, THOMAS M., SINGH, SHIV K., ELLENRIEDER, VOLKER
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626431/
https://ncbi.nlm.nih.gov/pubmed/22079596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.11.001
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