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Ex Vivo Red Blood Cell Hemolysis Assay for the Evaluation of pH-responsive Endosomolytic Agents for Cytosolic Delivery of Biomacromolecular Drugs

Phospholipid bilayers that constitute endo-lysosomal vesicles can pose a barrier to delivery of biologic drugs to intracellular targets. To overcome this barrier, a number of synthetic drug carriers have been engineered to actively disrupt the endosomal membrane and deliver cargo into the cytoplasm....

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Evans, Brian C., Nelson, Christopher E., Yu, Shann S., Beavers, Kelsey R., Kim, Arnold J., Li, Hongmei, Nelson, Heather M., Giorgio, Todd D., Duvall, Craig L.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MyJove Corporation 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626231/
https://ncbi.nlm.nih.gov/pubmed/23524982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50166
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