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The efficiency of cytosolic drug delivery using pH-responsive endosomolytic polymers does not correlate with activation of the NLRP3 inflammasome

Inefficient cytosolic delivery has limited the development of many promising biomacromolecular drugs, a long-standing challenge that has prompted extensive development of drug carriers that facilitate endosomal escape. Although many such carriers have shown considerable promise for cytosolic deliver...

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Dettagli Bibliografici
Pubblicato in:Biomater Sci
Autori principali: Baljon, Jessalyn J., Dandy, Aamina, Wang-Bishop, Lihong, Wehbe, Mohamed, Jacobson, Max E., Wilson, John T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478565/
https://ncbi.nlm.nih.gov/pubmed/30843539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8bm01643g
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