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Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain

Glutamate receptor ion channels are membrane proteins that mediate excitatory synaptic transmission in the central nervous system of vertebrates. Insight into molecular mechanisms underlying glutamate receptor gating is limited by lack of structural information for receptors trapped in different con...

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Main Authors: Schauder, David M., Kuybeda, Oleg, Zhang, Jinjin, Klymko, Katherine, Bartesaghi, Alberto, Borgnia, Mario J., Mayer, Mark L., Subramaniam, Sriram
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625259/
https://ncbi.nlm.nih.gov/pubmed/23530186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217549110
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