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Structural mechanism of glutamate receptor activation and desensitization
Ionotropic glutamate receptors are ligand-gated ion channels that mediate excitatory synaptic transmission in the vertebrate brain. To better understand how structural changes gate ion flux across the membrane, we trapped AMPA and kainate receptor subtypes in their major functional states and analyz...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4199900/ https://ncbi.nlm.nih.gov/pubmed/25119039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13603 |
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