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Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain

Glutamate receptor ion channels are membrane proteins that mediate excitatory synaptic transmission in the central nervous system of vertebrates. Insight into molecular mechanisms underlying glutamate receptor gating is limited by lack of structural information for receptors trapped in different con...

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Bibliografische gegevens
Hoofdauteurs: Schauder, David M., Kuybeda, Oleg, Zhang, Jinjin, Klymko, Katherine, Bartesaghi, Alberto, Borgnia, Mario J., Mayer, Mark L., Subramaniam, Sriram
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625259/
https://ncbi.nlm.nih.gov/pubmed/23530186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217549110
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