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Chaperonins Fight Aminoglycoside-induced Protein Misfolding and Promote Short-term Tolerance in Escherichia coli

For almost half of a century, we have known that aminoglycoside antibiotics corrupt ribosomes, causing translational misreading, yet it remains unclear whether or not misreading triggers protein misfolding, and possible effects of chaperone action on drug susceptibilities are poorly understood. Here...

詳細記述

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書誌詳細
主要な著者: Goltermann, Lise, Good, Liam, Bentin, Thomas
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624430/
https://ncbi.nlm.nih.gov/pubmed/23447537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420380
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