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Chaperonins Fight Aminoglycoside-induced Protein Misfolding and Promote Short-term Tolerance in Escherichia coli

For almost half of a century, we have known that aminoglycoside antibiotics corrupt ribosomes, causing translational misreading, yet it remains unclear whether or not misreading triggers protein misfolding, and possible effects of chaperone action on drug susceptibilities are poorly understood. Here...

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Bibliografische gegevens
Hoofdauteurs: Goltermann, Lise, Good, Liam, Bentin, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624430/
https://ncbi.nlm.nih.gov/pubmed/23447537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420380
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