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Chaperonins Fight Aminoglycoside-induced Protein Misfolding and Promote Short-term Tolerance in Escherichia coli

For almost half of a century, we have known that aminoglycoside antibiotics corrupt ribosomes, causing translational misreading, yet it remains unclear whether or not misreading triggers protein misfolding, and possible effects of chaperone action on drug susceptibilities are poorly understood. Here...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Goltermann, Lise, Good, Liam, Bentin, Thomas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624430/
https://ncbi.nlm.nih.gov/pubmed/23447537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420380
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