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Genetic Basis of Persister Tolerance to Aminoglycosides in Escherichia coli

Persisters are dormant variants that form a subpopulation of drug-tolerant cells largely responsible for the recalcitrance of chronic infections. However, our understanding of the genetic basis of antibiotic tolerance remains incomplete. In this study, we applied transposon sequencing (Tn-Seq) to sy...

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Vydáno v:mBio
Hlavní autoři: Shan, Yue, Lazinski, David, Rowe, Sarah, Camilli, Andrew, Lewis, Kim
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453570/
https://ncbi.nlm.nih.gov/pubmed/25852159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00078-15
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