ATP-Dependent Persister Formation in Escherichia coli

Persisters are dormant variants that form a subpopulation of cells tolerant to antibiotics. Persisters are largely responsible for the recalcitrance of chronic infections to therapy. In Escherichia coli, one widely accepted model of persister formation holds that stochastic accumulation of ppGpp cau...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:mBio
Prif Awduron: Shan, Yue, Brown Gandt, Autumn, Rowe, Sarah E., Deisinger, Julia P., Conlon, Brian P., Lewis, Kim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296605/
https://ncbi.nlm.nih.gov/pubmed/28174313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02267-16
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