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Chaperonins Fight Aminoglycoside-induced Protein Misfolding and Promote Short-term Tolerance in Escherichia coli
For almost half of a century, we have known that aminoglycoside antibiotics corrupt ribosomes, causing translational misreading, yet it remains unclear whether or not misreading triggers protein misfolding, and possible effects of chaperone action on drug susceptibilities are poorly understood. Here...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624430/ https://ncbi.nlm.nih.gov/pubmed/23447537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420380 |
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