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Chaperonins Fight Aminoglycoside-induced Protein Misfolding and Promote Short-term Tolerance in Escherichia coli

For almost half of a century, we have known that aminoglycoside antibiotics corrupt ribosomes, causing translational misreading, yet it remains unclear whether or not misreading triggers protein misfolding, and possible effects of chaperone action on drug susceptibilities are poorly understood. Here...

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Detaylı Bibliyografya
Asıl Yazarlar: Goltermann, Lise, Good, Liam, Bentin, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624430/
https://ncbi.nlm.nih.gov/pubmed/23447537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420380
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