Lataa...

E6AP/UBE3A Ubiquitin Ligase Harbors Two E2∼ubiquitin Binding Sites

By exploiting (125)I-polyubiquitin chain formation as a functional readout of enzyme activity, we have quantitatively examined the mechanism of human E6AP/UBE3A for the first time. Initial rate studies identify UbcH7 as the cognate E2 carrier protein for E6AP, although related Ubc5 isoforms and the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ronchi, Virginia P., Klein, Jennifer M., Haas, Arthur L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624418/
https://ncbi.nlm.nih.gov/pubmed/23439649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.458059
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!