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Arsenic Trioxide Stabilizes Accumulations of Adeno-Associated Virus Virions at the Perinuclear Region, Increasing Transduction In Vitro and In Vivo

Interactions with cellular stress pathways are central to the life cycle of many latent viruses. Here, we utilize adeno-associated virus (AAV) as a model to study these interactions, as previous studies have demonstrated that cellular stressors frequently increase transduction of recombinant AAV (rA...

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Hlavní autoři: Mitchell, Angela M., Li, Chengwen, Samulski, R. Jude
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624361/
https://ncbi.nlm.nih.gov/pubmed/23408604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03443-12
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