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Arsenic Trioxide Stabilizes Accumulations of Adeno-Associated Virus Virions at the Perinuclear Region, Increasing Transduction In Vitro and In Vivo

Interactions with cellular stress pathways are central to the life cycle of many latent viruses. Here, we utilize adeno-associated virus (AAV) as a model to study these interactions, as previous studies have demonstrated that cellular stressors frequently increase transduction of recombinant AAV (rA...

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Detalhes bibliográficos
Main Authors: Mitchell, Angela M., Li, Chengwen, Samulski, R. Jude
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624361/
https://ncbi.nlm.nih.gov/pubmed/23408604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03443-12
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