Selective Serotonin Reuptake Inhibitor Fluoxetine Inhibits Replication of Human Enteroviruses B and D by Targeting Viral Protein 2C

Although the genus Enterovirus contains many important human pathogens, there is no licensed drug for either the treatment or the prophylaxis of enterovirus infections. We report that fluoxetine (Prozac)—a selective serotonin reuptake inhibitor—inhibits the replication of human enterovirus B (HEV-B)...

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Main Authors: Ulferts, Rachel, van der Linden, Lonneke, Thibaut, Hendrik Jan, Lanke, Kjerstin H. W., Leyssen, Pieter, Coutard, Bruno, De Palma, Armando M., Canard, Bruno, Neyts, Johan, van Kuppeveld, Frank J. M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623316/
https://ncbi.nlm.nih.gov/pubmed/23335743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02084-12
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