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A Novel, Broad-Spectrum Inhibitor of Enterovirus Replication That Targets Host Cell Factor Phosphatidylinositol 4-Kinase IIIβ

Despite their high clinical and socioeconomic impacts, there is currently no approved antiviral therapy for the prophylaxis or treatment of enterovirus infections. Here we report on a novel inhibitor of enterovirus replication, compound 1, 2-fluoro-4-(2-methyl-8-(3-(methylsulfonyl)benzylamino)imidaz...

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Bibliografski detalji
Glavni autori: van der Schaar, Hilde M., Leyssen, Pieter, Thibaut, Hendrik J., de Palma, Armando, van der Linden, Lonneke, Lanke, Kjerstin H. W., Lacroix, Céline, Verbeken, Erik, Conrath, Katja, MacLeod, Angus M., Mitchell, Dale R., Palmer, Nicholas J., van de Poël, Hervé, Andrews, Martin, Neyts, Johan, van Kuppeveld, Frank J. M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811463/
https://ncbi.nlm.nih.gov/pubmed/23896472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01175-13
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