A Novel, Broad-Spectrum Inhibitor of Enterovirus Replication That Targets Host Cell Factor Phosphatidylinositol 4-Kinase IIIβ

Despite their high clinical and socioeconomic impacts, there is currently no approved antiviral therapy for the prophylaxis or treatment of enterovirus infections. Here we report on a novel inhibitor of enterovirus replication, compound 1, 2-fluoro-4-(2-methyl-8-(3-(methylsulfonyl)benzylamino)imidaz...

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Bibliografiska uppgifter
Huvudupphovsmän: van der Schaar, Hilde M., Leyssen, Pieter, Thibaut, Hendrik J., de Palma, Armando, van der Linden, Lonneke, Lanke, Kjerstin H. W., Lacroix, Céline, Verbeken, Erik, Conrath, Katja, MacLeod, Angus M., Mitchell, Dale R., Palmer, Nicholas J., van de Poël, Hervé, Andrews, Martin, Neyts, Johan, van Kuppeveld, Frank J. M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811463/
https://ncbi.nlm.nih.gov/pubmed/23896472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01175-13
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