NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents

AIMS/HYPOTHESIS: The activation of NADPH oxidase has been implicated in NEFA-induced beta cell dysfunction. However, the causal role of this activation in vivo remains unclear. Here, using rodents, we investigated whether pharmacological or genetic inhibition of NADPH oxidase could prevent NEFA-indu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Koulajian, K., Desai, T., Liu, G. C., Ivovic, A., Patterson, J. N., Tang, C., El-Benna, J., Joseph, J. W., Scholey, J. W., Giacca, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622749/
https://ncbi.nlm.nih.gov/pubmed/23429921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-013-2858-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados