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Agonistic anti-CD40 induces thyrocyte proliferation and promotes thyroid autoimmunity by increasing CD40 expression on thyroid epithelial cells

CD40 is expressed on cells of the immune system and in some tissues that are targets for autoimmune-mediated damage. It is not known if CD40 expression in target tissues plays a role in the pathology of autoimmune diseases. This study shows that agonistic anti-CD40 induces strong and sustained proli...

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Bibliografske podrobnosti
Main Authors: Kayes, Timothy, Fang, Yujiang, Yu, Shiguang, Downey, Edward, Wang, Shufang, Braley-Mullen, Helen
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622184/
https://ncbi.nlm.nih.gov/pubmed/23509363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202929
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