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Culture Promotes Transfer of Thyroid Epithelial Cell Hyperplasia and Proliferation by Reducing Regulatory T Cell Numbers
IFN-γ(−/−) NOD.H-2h4 mice develop a spontaneous autoimmune thyroid disease, thyroid epithelial cell hyperplasia and proliferation (TEC H/P) when given NaI in their water for 7+ mo. TEC H/P can be transferred to IFN-γ(−/−) SCID mice by splenocytes from mice with severe (4–5+) disease, and transfer of...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834243/ https://ncbi.nlm.nih.gov/pubmed/24135055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2013.09.003 |
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