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CD8+ T cells induce thyroid epithelial cell hyperplasia and fibrosis()

CD8+ T cells can be important effector cells in autoimmune inflammation, generally because they can damage target cells by cytotoxicity. This study shows that activated CD8+ T cells induce thyroid epithelial cell hyperplasia and proliferation (TEC H/P) and fibrosis in IFN-γ−/− NOD.H-2h4 SCID mice in...

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Detalhes bibliográficos
Main Authors: Yu, Shiguang, Fang, Yujiang, Sharav, Tumenjargal, Sharp, Gordon C., Braley-Mullen, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280124/
https://ncbi.nlm.nih.gov/pubmed/21220693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002884
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