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Agonistic anti-CD40 induces thyrocyte proliferation and promotes thyroid autoimmunity by increasing CD40 expression on thyroid epithelial cells

CD40 is expressed on cells of the immune system and in some tissues that are targets for autoimmune-mediated damage. It is not known if CD40 expression in target tissues plays a role in the pathology of autoimmune diseases. This study shows that agonistic anti-CD40 induces strong and sustained proli...

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Detalhes bibliográficos
Main Authors: Kayes, Timothy, Fang, Yujiang, Yu, Shiguang, Downey, Edward, Wang, Shufang, Braley-Mullen, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622184/
https://ncbi.nlm.nih.gov/pubmed/23509363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202929
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