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Generation of Stable Human Cell Lines with Tetracycline-inducible (Tet-on) shRNA or cDNA Expression

A major approach in the field of mammalian cell biology is the manipulation of the expression of genes of interest in selected cell lines, with the aim to reveal one or several of the gene's function(s) using transient/stable overexpression or knockdown of the gene of interest. Unfortunately, f...

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Detalhes bibliográficos
Main Authors: Gomez-Martinez, Marta, Schmitz, Debora, Hergovich, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622098/
https://ncbi.nlm.nih.gov/pubmed/23486277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50171
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