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The Hedgehog Receptor Patched1 in T Cells Is Dispensable for Adaptive Immunity in Mice
Hedgehog (Hh) signaling modulates T cell development and function but its exact role remains a matter of debate. To further address this issue we made use of conditional knock-out mice in which the Hh receptor Patched1 (Ptch) is inactivated in the T cell lineage. Thymocyte development was moderately...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3620050/ https://ncbi.nlm.nih.gov/pubmed/23577186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061034 |
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