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A Functional and Putative Physiological Role of Calcitriol in Patched1/Smoothened Interaction
The Patched1 (Ptch)-mediated inhibition of Smoothened (Smo) is still an open question. However, a direct Ptch/Smo interaction has been excluded, Smo modulators were identified, but the endogenous signal transmitting molecule remains undiscovered. Here, we demonstrate that calcitriol, the hormonally...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4528127/ https://ncbi.nlm.nih.gov/pubmed/26126827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.646141 |
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