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Targeting a DNA Binding Motif of the EVI1 Protein by a Pyrrole–Imidazole Polyamide
[Image: see text] The zinc finger protein EVI1 is causally associated with acute myeloid leukemogenesis, and inhibition of its function with a small molecule therapeutic may provide effective therapy for EVI1-expressing leukemias. In this paper we describe the development of a pyrrole–imidazole poly...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3619939/ https://ncbi.nlm.nih.gov/pubmed/22039883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200962u |
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