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In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography

The biodistribution profiles in mice of two pyrrole-imidazole polyamides were determined by PET. Pyrrole-imidazole polyamides are a class of small molecules that can be programmed to bind a broad repertoire of DNA sequences, disrupt transcription factor-DNA interfaces, and modulate gene expression p...

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Bibliografische gegevens
Hoofdauteurs: Harki, Daniel A., Satyamurthy, Nagichettiar, Stout, David B., Phelps, Michael E., Dervan, Peter B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529060/
https://ncbi.nlm.nih.gov/pubmed/18753620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806308105
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