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Solution-Phase Synthesis of Pyrrole-Imidazole Polyamides

Pyrrole-imidazole polyamides are DNA binding molecules that are programmable for a large repertoire of DNA sequences. Typical syntheses of this class of heterocyclic oligomers rely on solid-phase methods. Solid-phase methodologies offer rapid assembly on a micromole scale sufficient for biophysical...

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Bibliografiske detaljer
Main Authors: Chenoweth, David M., Harki, Daniel A., Dervan, Peter B.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689157/
https://ncbi.nlm.nih.gov/pubmed/19413320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja901307m
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