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An algorithmic approach for breakage-fusion-bridge detection in tumor genomes
Breakage-fusion-bridge (BFB) is a mechanism of genomic instability characterized by the joining and subsequent tearing apart of sister chromatids. When this process is repeated during multiple rounds of cell division, it leads to patterns of copy number increases of chromosomal segments as well as f...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3619374/ https://ncbi.nlm.nih.gov/pubmed/23503850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220977110 |
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