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An algorithmic approach for breakage-fusion-bridge detection in tumor genomes
Breakage-fusion-bridge (BFB) is a mechanism of genomic instability characterized by the joining and subsequent tearing apart of sister chromatids. When this process is repeated during multiple rounds of cell division, it leads to patterns of copy number increases of chromosomal segments as well as f...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3619374/ https://ncbi.nlm.nih.gov/pubmed/23503850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220977110 |
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