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An algorithmic approach for breakage-fusion-bridge detection in tumor genomes

Breakage-fusion-bridge (BFB) is a mechanism of genomic instability characterized by the joining and subsequent tearing apart of sister chromatids. When this process is repeated during multiple rounds of cell division, it leads to patterns of copy number increases of chromosomal segments as well as f...

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Detaylı Bibliyografya
Asıl Yazarlar: Zakov, Shay, Kinsella, Marcus, Bafna, Vineet
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619374/
https://ncbi.nlm.nih.gov/pubmed/23503850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220977110
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