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Sensitive gene fusion detection using ambiguously mapping RNA-Seq read pairs
Motivation: Paired-end whole transcriptome sequencing provides evidence for fusion transcripts. However, due to the repetitiveness of the transcriptome, many reads have multiple high-quality mappings. Previous methods to find gene fusions either ignored these reads or required additional longer sing...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072550/ https://ncbi.nlm.nih.gov/pubmed/21330288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr085 |
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