Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity

It has long been known that rearrangements of chromosomes through breakage-fusion-bridge (BFB) cycles may cause variability of phenotypic and genetic traits within a cell population. Because intercellular heterogeneity is often found in neoplastic tissues, we investigated the occurrence of BFB event...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gisselsson, David, Pettersson, Louise, Höglund, Mattias, Heidenblad, Markus, Gorunova, Ludmila, Wiegant, Joop, Mertens, Fredrik, Dal Cin, Paola, Mitelman, Felix, Mandahl, Nils
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2000
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC25833/
https://ncbi.nlm.nih.gov/pubmed/10805796
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