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Reconstructing Breakage Fusion Bridge Architectures Using Noisy Copy Numbers

The Breakage Fusion Bridge (BFB) process is a key marker for genomic instability, producing highly rearranged genomes in relatively small numbers of cell cycles. While the process itself was observed during the late 1930s, little is known about the extent of BFB in tumor genome evolution. Moreover,...

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Bibliografiska uppgifter
I publikationen:J Comput Biol
Huvudupphovsmän: Zakov, Shay, Bafna, Vineet
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449712/
https://ncbi.nlm.nih.gov/pubmed/26020441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2014.0166
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