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Reconstructing Breakage Fusion Bridge Architectures Using Noisy Copy Numbers
The Breakage Fusion Bridge (BFB) process is a key marker for genomic instability, producing highly rearranged genomes in relatively small numbers of cell cycles. While the process itself was observed during the late 1930s, little is known about the extent of BFB in tumor genome evolution. Moreover,...
Guardat en:
| Publicat a: | J Comput Biol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Mary Ann Liebert, Inc.
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4449712/ https://ncbi.nlm.nih.gov/pubmed/26020441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2014.0166 |
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