Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability

Suppressor of variegation 3–9 homolog 1 (SUV39H1), a histone methyltransferase, catalyzes histone 3 lysine 9 trimethylation and is involved in heterochromatin organization and genome stability. However, the mechanism for regulation of the enzymatic activity of SUV39H1 in cancer cells is not yet well...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Wang, Donglai, Zhou, Jingyi, Liu, Xiangyu, Lu, Danyu, Shen, Changchun, Du, Yipeng, Wei, Fu-Zheng, Song, Boyan, Lu, Xiaopeng, Yu, Yu, Wang, Lina, Zhao, Ying, Wang, Haiying, Yang, Yang, Akiyama, Yoshimitsu, Zhang, Hongquan, Zhu, Wei-Guo
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2013
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619320/
https://ncbi.nlm.nih.gov/pubmed/23509280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216596110
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk