Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability

Suppressor of variegation 3–9 homolog 1 (SUV39H1), a histone methyltransferase, catalyzes histone 3 lysine 9 trimethylation and is involved in heterochromatin organization and genome stability. However, the mechanism for regulation of the enzymatic activity of SUV39H1 in cancer cells is not yet well...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Donglai, Zhou, Jingyi, Liu, Xiangyu, Lu, Danyu, Shen, Changchun, Du, Yipeng, Wei, Fu-Zheng, Song, Boyan, Lu, Xiaopeng, Yu, Yu, Wang, Lina, Zhao, Ying, Wang, Haiying, Yang, Yang, Akiyama, Yoshimitsu, Zhang, Hongquan, Zhu, Wei-Guo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619320/
https://ncbi.nlm.nih.gov/pubmed/23509280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216596110
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