A glue for heterochromatin maintenance: stable SUV39H1 binding to heterochromatin is reinforced by the SET domain

Trimethylation of histone H3 lysine 9 and the subsequent binding of heterochromatin protein 1 (HP1) mediate the formation and maintenance of pericentromeric heterochromatin. Trimethylation of H3K9 is governed by the histone methyltransferase SUV39H1. Recent studies of HP1 dynamics revealed that HP1...

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Main Authors: Krouwels, Ilke M., Wiesmeijer, Karien, Abraham, Tsion E., Molenaar, Chris, Verwoerd, Nico P., Tanke, Hans J., Dirks, Roeland W.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2005
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171490/
https://ncbi.nlm.nih.gov/pubmed/16103223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200502154
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