RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin

Heterochromatin formed by the SUV39 histone methyltransferases represses transcription from repetitive DNA sequences and ensures genomic stability. How SUV39 enzymes localize to their target genomic loci remains unclear. Here, we demonstrate that chromatin-associated RNA contributes to the stable as...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Johnson, Whitney L, Yewdell, William T, Bell, Jason C, McNulty, Shannon M, Duda, Zachary, O’Neill, Rachel J, Sullivan, Beth A, Straight, Aaron F
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538822/
https://ncbi.nlm.nih.gov/pubmed/28760200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25299
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker