RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin

Heterochromatin formed by the SUV39 histone methyltransferases represses transcription from repetitive DNA sequences and ensures genomic stability. How SUV39 enzymes localize to their target genomic loci remains unclear. Here, we demonstrate that chromatin-associated RNA contributes to the stable as...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Johnson, Whitney L, Yewdell, William T, Bell, Jason C, McNulty, Shannon M, Duda, Zachary, O’Neill, Rachel J, Sullivan, Beth A, Straight, Aaron F
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2017
Aiheet:
Cell Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538822/
https://ncbi.nlm.nih.gov/pubmed/28760200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25299
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