RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin

Heterochromatin formed by the SUV39 histone methyltransferases represses transcription from repetitive DNA sequences and ensures genomic stability. How SUV39 enzymes localize to their target genomic loci remains unclear. Here, we demonstrate that chromatin-associated RNA contributes to the stable as...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Johnson, Whitney L, Yewdell, William T, Bell, Jason C, McNulty, Shannon M, Duda, Zachary, O’Neill, Rachel J, Sullivan, Beth A, Straight, Aaron F
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538822/
https://ncbi.nlm.nih.gov/pubmed/28760200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25299
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