RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin

Heterochromatin formed by the SUV39 histone methyltransferases represses transcription from repetitive DNA sequences and ensures genomic stability. How SUV39 enzymes localize to their target genomic loci remains unclear. Here, we demonstrate that chromatin-associated RNA contributes to the stable as...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Johnson, Whitney L, Yewdell, William T, Bell, Jason C, McNulty, Shannon M, Duda, Zachary, O’Neill, Rachel J, Sullivan, Beth A, Straight, Aaron F
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2017
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5538822/
https://ncbi.nlm.nih.gov/pubmed/28760200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25299
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