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Division of labor between the chromodomains of HP1 and Suv39 methylase enables coordination of heterochromatin spread

In Schizosaccharomyces pombe, heterochromatin spread, which is marked by histone H3 lysine 9 methylation (H3K9me), requires the chromodomains (CD) of the H3K9 methylase Suv39/Clr4 and the HP1/Swi6 protein. It is unclear how the actions of these two H3K9 methylation recognizing CDs are coordinated. W...

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Hlavní autoři: Al-Sady, Bassem, Madhani, Hiten D., Narlikar, Geeta J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752401/
https://ncbi.nlm.nih.gov/pubmed/23849629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.06.013
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