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Intrinsic Toxicity of Unchecked Heterochromatin Spread Is Suppressed by Redundant Chromatin Boundary Functions in Schizosacchromyces pombe

Effective boundary mechanisms halt the spread of repressive histone methylation. In the fission yeast Schizosacchromyces pombe, two factors/elements required for boundary function have been described, the jmjC protein Epe1 and binding sites for the RNA polymerase III transcription factor TFIIIC. Per...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Garcia, Jennifer F., Al-Sady, Bassem, Madhani, Hiten D.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502379/
https://ncbi.nlm.nih.gov/pubmed/25957277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.018663
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