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Intrinsic Toxicity of Unchecked Heterochromatin Spread Is Suppressed by Redundant Chromatin Boundary Functions in Schizosacchromyces pombe

Effective boundary mechanisms halt the spread of repressive histone methylation. In the fission yeast Schizosacchromyces pombe, two factors/elements required for boundary function have been described, the jmjC protein Epe1 and binding sites for the RNA polymerase III transcription factor TFIIIC. Per...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Garcia, Jennifer F., Al-Sady, Bassem, Madhani, Hiten D.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502379/
https://ncbi.nlm.nih.gov/pubmed/25957277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.018663
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