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Chromodomain-mediated oligomerization of HP1 suggests a nucleosome bridging mechanism for heterochromatin assembly

HP1 proteins are central to the assembly and spread of heterochromatin containing histone H3K9 methylation. The chromodomain (CD) of HP1 proteins specifically recognizes the methyl mark on H3 peptides, but the same extent of specificity is not observed within chromatin. The chromoshadow domain of HP...

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Detalhes bibliográficos
Main Authors: Canzio, Daniele, Chang, Evelyn Y., Shankar, Smita, Kuchenbecker, Kristopher M., Simon, Matthew D., Madhani, Hiten D., Narlikar, Geeta J., Sady, Bassem Al
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752404/
https://ncbi.nlm.nih.gov/pubmed/21211724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.12.016
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