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The methyltransferase Suv39h1 links the SUMO pathway to HP1α marking at pericentric heterochromatin

The trimethylation of histone H3 on lysine 9 (H3K9me3) – a mark recognized by HP1 that depends on the Suv39h lysine methyltransferases (KMTs) – has provided a basis for the reader/writer model to explain HP1 accumulation at pericentric heterochromatin in mammals. Here, we identify the Suv39h1 paralo...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Maison, Christèle, Bailly, Delphine, Quivy, Jean-Pierre, Almouzni, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960310/
https://ncbi.nlm.nih.gov/pubmed/27426629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12224
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