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The methyltransferase Suv39h1 links the SUMO pathway to HP1α marking at pericentric heterochromatin
The trimethylation of histone H3 on lysine 9 (H3K9me3) – a mark recognized by HP1 that depends on the Suv39h lysine methyltransferases (KMTs) – has provided a basis for the reader/writer model to explain HP1 accumulation at pericentric heterochromatin in mammals. Here, we identify the Suv39h1 paralo...
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| Publié dans: | Nat Commun |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4960310/ https://ncbi.nlm.nih.gov/pubmed/27426629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12224 |
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