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Establishment and Characterization of the First Pediatric Adrenocortical Carcinoma Xenograft Model Identifies Topotecan as a Potential Chemotherapeutic Agent

PURPOSE: Pediatric adrenocortical carcinoma (ACC) is a rare and highly aggressive malignancy. Conventional chemotherapeutic agents have shown limited utility and are largely ineffective in treating children with advanced ACC. The lack of cell lines and animal models of pediatric ACC has hampered the...

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Bibliografiset tiedot
Päätekijät: Pinto, Emilia M., Morton, Christopher, Rodriguez-Galindo, Carlos, McGregor, Lisa, Davidoff, Andrew M., Mercer, Kimberly, Debelenko, Larisa V., Billups, Catherine, Ribeiro, Raul C., Zambetti, Gerard P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618554/
https://ncbi.nlm.nih.gov/pubmed/23406775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3354
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